Zepbound Online · AI Primary Care for Weight Management & OSA

How it works

Chart in, eligibility checked against the right Zepbound indication, branded medication sent to your pharmacy, trend tracked weekly.

Connect your records and CPAP data

Clara auto-syncs your records from 150,000+ doctors' offices, hospitals, clinics, labs, and wearables. The AI reads BMI, comorbidity list, sleep study results or CPAP AHI, and thyroid/pancreatitis history against the Zepbound label before anything is prescribed. Free to start.

Prescription on the right indication

If you have OSA with obesity, Clara writes Zepbound on the OSA indication — which often improves coverage. If weight is the primary indication, it goes through on the obesity indication. A licensed physician signs the prescription before it reaches your pharmacy.

Titrate to 15 mg and watch the trend

Zepbound titrates 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg in 2.5 mg increments at least four weeks apart⁴. Clara watches your weight trend, GI tolerability, AHI on CPAP downloads, and wearable sleep architecture between every step.

Dosing

The Zepbound titration ladder for both indications.

Rx · Initiation

2.5 mg weeks 1–4

Titration dose only, not therapeutic on its own. Clara uses these four weeks to watch how your gastrointestinal system handles the molecule before stepping up.

4 wks

Then 5 mg

Rx · Step-up

5 → 7.5 → 10 mg

Each step at least four weeks apart. Clara watches weight trend, AHI changes if you're on CPAP, and side-effect frequency. Holds at the prior dose if your body isn't ready for the next step.

3 steps

4 weeks each

Rx · High dose

12.5 → 15 mg weekly

The maintenance doses studied in SURMOUNT-1 (weight management) and SURMOUNT-OSA (sleep apnea)⁴. Most patients stay below 15 mg if their trend hits target sooner.

15 mg

Maximum maintenance dose

Rx · Alternative

Wegovy (semaglutide)

If Zepbound isn't covered or isn't tolerated, Wegovy is the on-label semaglutide alternative for chronic weight management. Clara reads both labels against your chart and recommends whichever is more appropriate.

On-label alternative

Why Clara

Branded Zepbound on the right indication, with an AI reading your sleep data and your scale.

	Clara	Hims & Hers	Lemonaid Health	Your doctor
OSA indication recognized and used	✓ Reads CPAP, sleep study, wearable AHI	Weight-only intake	Weight program only	If your doctor knows about it
24/7 AI clinical chat	✓ Unlimited	Async Care Team messaging	Async provider messaging	✗
Full-chart eligibility check on every titration	✓	Single-condition intake	Per-category intake	Depends on visit length
Cost to start chatting	Free	$39 first-month membership	Brief eligibility assessment	$150+ copay per visit
Membership cost	From $25/mo cash-pay (HSA/FSA eligible); medication billed separately, may be covered by your insurance	$149/mo after first month; medication bundled, cash-pay	$49/mo; medication billed separately, cash-pay	Per-visit copay
Branded FDA-approved Zepbound	✓	Sells compounded tirzepatide alongside branded Zepbound, cash-pay	Sells compounded tirzepatide	✓
Prescription may be covered by your insurance	✓	✗	✗	✓
Cross-condition primary care	✓ BP, lipids, thyroid, sleep, everything	Single-category	Partial, separate intakes	✓
Labs and biomarkers included in membership	Up to 108 on Concierge	Extra cost	Extra cost	Copay per test

The AI difference

Zepbound's OSA indication only matters if someone is reading your sleep data.

Zepbound was the first GLP-1 FDA-approved for moderate-to-severe obstructive sleep apnea in adults with obesity⁴. That indication unlocks coverage paths that the obesity-only indication doesn't always reach. But the indication is only useful if a doctor is actually reading your sleep study, your CPAP downloads, and your wearable sleep data. That's the AI's job.

Reads your CPAP and sleep study

Clara ingests your sleep study report and downloads your CPAP AHI weekly if you connect ResMed myAir or Philips DreamMapper. The OSA indication for Zepbound requires moderate-to-severe disease, which is an AHI threshold the AI can verify before prescribing.

Right indication, better coverage path

Insurers often cover Zepbound for OSA where they decline obesity-only coverage. Clara writes the script on the indication that's most clinically and financially appropriate for you, rather than defaulting to obesity for everyone.

Watches AHI alongside weight

SURMOUNT-OSA showed AHI reductions alongside weight loss⁴. Clara tracks both. If your AHI improves but weight plateaus, or vice versa, the AI surfaces the mismatch and queues a clinical review before the next step-up.

Common questions

Zepbound questions patients actually search for.

What does Clara cost?

It's free to connect your medical records and start chatting with Clara. If you want Clara to provide medical advice, prescribe medications, or order labs, plans start at $25/month. All plans are HSA/FSA eligible. The cost of Zepbound and lab work is separate and may be covered by your existing insurance, unlike the cash-pay model most GLP-1 telehealth brands use.

Am I eligible for Zepbound?

Zepbound is FDA-approved as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with BMI ≥30, or BMI ≥27 with at least one weight-related comorbidity (hypertension, type 2 diabetes, or dyslipidemia), and separately for moderate-to-severe obstructive sleep apnea in adults with obesity⁴. Clara reads your BMI, comorbidity list, sleep study/CPAP data, pregnancy plans, and thyroid family history to confirm eligibility on the appropriate indication.

What's the difference between Zepbound and Mounjaro?

Same molecule (tirzepatide), different FDA-approved indications. Mounjaro is on-label for type 2 diabetes. Zepbound is on-label for chronic weight management and for moderate-to-severe OSA with obesity⁴. If weight or sleep apnea is your indication and you don't have T2D, Zepbound is the correct script and far more likely to be covered.

How does Zepbound compare to Wegovy?

Different molecules, both FDA-approved for chronic weight management. Wegovy is semaglutide (GLP-1 agonist). Zepbound is tirzepatide (dual GIP/GLP-1 agonist). In the SURMOUNT-5 head-to-head trial, tirzepatide produced larger average weight loss than semaglutide. But Wegovy is also on-label for adolescents aged 12+ and Zepbound has the OSA indication that Wegovy doesn't. Clara picks based on your chart, your insurance formulary, and your tolerance.

I have sleep apnea. Will Zepbound replace my CPAP?

Probably not, at least not initially. Zepbound is FDA-approved as an adjunct, not a replacement, for OSA. As your AHI improves with weight loss, your sleep specialist may eventually wean or retire CPAP. Clara works alongside your sleep medicine clinician — and refers you to one if you don't have a current sleep study.

What about Zepbound while pregnant or trying to conceive?

Zepbound should be discontinued at least two months before a planned pregnancy due to the long half-life of tirzepatide⁴. Clara asks about pregnancy plans during eligibility and flags this if your chart has recent obstetric or fertility notes.

What if I have a family history of medullary thyroid cancer?

Zepbound carries a boxed warning about thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)⁴. Clara asks explicitly about first-degree family history before any GLP-1 is drafted. If that flag is positive, Zepbound is off the table and Clara surfaces non-GLP-1 alternatives.

Is Clara a real medical practice?

Yes. Clara is licensed in all 50 states. Diagnoses, prescriptions, and lab orders are reviewed and signed off by licensed physicians. Clara's AI handles intake, continuous monitoring, and follow-up; the clinical sign-off happens at the end.

How is this different from a weight-loss DTC brand?

Can your old doctor or a DTC brand read your full chart, your CPAP downloads, your wearable sleep data, and your labs every time they look at your prescription? Clara can. A DTC brand sees a narrow weight-only intake. Clara is full primary care with a longitudinal view, which is precisely the piece both a 15-minute clinic visit and a single-condition storefront miss.

Can I use my insurance, HSA, or FSA?

Clara's membership itself is cash-pay, not billed through insurance, but every plan is HSA/FSA eligible so you can pay it with pre-tax dollars. Zepbound prescriptions Clara writes go to your pharmacy and may be covered by your plan — particularly under the OSA indication if applicable. Ad-hoc labs Clara orders may also be covered. Clara does not sell compounded tirzepatide.

What is my data used for? Is it private?

Clara is HIPAA compliant. Your records are used to personalize your care. They're not sold, and they're not used to train public AI models.

Can I use Clara for other health issues too?

Yes. One membership covers full primary care, not just Zepbound or weight loss. The same chat handles blood pressure, cholesterol, thyroid, annual labs, and longevity work. See the full longevity labs page.

Zepbound—the only GLP-1 FDA-approved for moderate-to-severe sleep apnea with obesity.