Clara reads your labs, medications, and wearable data together to surface what may actually be driving your fatigue. A licensed physician reviews every clinical finding before any action is taken.
Get started See possible causesValues and scenarios shown are illustrative examples only. Clara identifies patterns for physician review — it does not diagnose from symptoms alone.
Clara auto-syncs your medical records from 150,000+ doctors' offices, hospitals, labs, and pharmacies: every prior lab, every prescription, every diagnosis. Wearable data syncs automatically on Standard and Concierge plans. Free to start, no credit card.
Fatigue is the starting point, not the conclusion. Clara reads your full chart — recent labs, medications, wearable trends, prior diagnoses — and surfaces the most likely contributors rather than anchoring on the first plausible explanation. Many cases of fatigue involve more than one contributing factor.
When the chart points at something worth investigating, Clara orders the relevant labs and prepares a clinical summary for physician review. Every lab order is reviewed and signed by a licensed physician. Plans start at $25/mo. Labs on Standard and Concierge plans include the most common fatigue workup in one pass.
Your chart already has most of the context. Clara reads it so you don't have to start from scratch.
Get started Free to connect records. HSA and FSA eligible.Many cases of persistent fatigue are caused by something treatable once identified. The conditions below are the most common causes Clara looks for — reading them together in context rather than evaluating each in isolation.
Low ferritin (iron stores) is one of the most commonly missed causes of fatigue, particularly in women of reproductive age. Ferritin can be depleted well before hemoglobin falls into the anemia range, meaning a standard CBC can look normal while iron stores are significantly low.
Fatigue is the most common presenting symptom of an underactive thyroid. A TSH in the "normal" reference range doesn't always mean the thyroid is optimally functioning — particularly in patients with Hashimoto's, where antibody levels and Free T4 add important context.
How Clara manages hypothyroidism →Low 25-OH vitamin D is widespread and directly associated with fatigue, muscle weakness, and low mood. It is frequently missed on standard annual panels because it is not always included by default.
B12 deficiency causes fatigue, brain fog, and neurological symptoms. It is particularly common in patients on metformin, proton pump inhibitors, or those with reduced dietary intake. Low-normal B12 levels (200–400 pg/mL) can still be functionally insufficient for some patients.
Hormonal changes during perimenopause frequently cause fatigue, sleep disruption, and cognitive fog — often years before periods stop. These symptoms often go unrecognized or are attributed to stress or depression rather than the hormonal transition driving them.
Fatigue is a core symptom of both depression and anxiety. Clara runs a PHQ-9 screen and reads your symptom picture alongside your labs to distinguish mood-related fatigue from metabolic fatigue — the distinction matters for what comes next.
Fatigue is a common early sign of insulin resistance, often appearing years before HbA1c moves into the prediabetes range. Fasting insulin is a more sensitive early marker that a standard annual panel typically doesn't include.
How Clara manages diabetes and prediabetes →Sleep apnea is significantly underdiagnosed, particularly in women and in people without classic risk factors. Fatigue despite adequate sleep duration, wearable data showing fragmented sleep or elevated resting HR, and a BMI above 25 are all signals Clara watches for. Clara can queue a home sleep study when the pattern warrants it.
Fatigue is a side effect of many common medications including beta blockers, SSRIs, antihistamines, statins, and blood pressure medications. Clara reads your full medication list before concluding that fatigue is unexplained.
If your fatigue is accompanied by chest pain or pressure, shortness of breath at rest, sudden severe headache, fainting or near-fainting, one-sided weakness or slurred speech, or coughing or vomiting blood, call 911 or go to your nearest emergency room immediately. Clara is not an emergency service. For life-threatening symptoms, always call 911.
A normal TSH with low ferritin and low-normal B12 is a different clinical picture than a normal TSH alone. Clara reads every result in your chart against your current medications and wearable trends rather than evaluating each lab in isolation.
Many cases of fatigue have more than one contributing factor. Iron deficiency and hypothyroidism can coexist. Depression and sleep apnea frequently occur together. Clara looks at the full picture before suggesting what to investigate next.
If your wearable shows fragmented sleep or an elevated resting HR alongside recent labs, that context also factors into what Clara surfaces for physician review.
| Clara | Symptom checker app | General telehealth | Your doctor | |
|---|---|---|---|---|
| Reads your full chart before responding | ✓ Auto-synced, 150,000+ sources | Symptom input only | Self-reported history | Within a single practice |
| Evaluates multiple causes at once | ✓ | Algorithm-ranked suggestions | Visit-by-visit | At visit, depends on time |
| Orders a full fatigue workup when cause is unclear | ✓ Physician-reviewed panel | ✗ | Limited panel | ✓ |
| Reads wearable data alongside labs | ✓ | ✗ | ✗ | ✗ |
| Monthly cost | $25–$150/mo · HSA/FSA eligible | Free to use | Varies | Per-visit copay |
| Biomarker panel included | ✓ Included in Standard and Concierge memberships | ✗ | Extra cost | Per-test copay |
| Physician-approved prescriptions and lab orders | ✓ | ✗ | ✓ | ✓ |
The answers are often already in your medical history. Clara puts them together.
Get started From $25/mo · HSA/FSA eligible · cash-pay.A clinician in a 15-minute visit reads the last panel. Clara reads every result you have ever had drawn, every medication you have been on, and every wearable reading in a single pass. That is not a time-management difference. It is a category-of-work difference. The AI handles the data; licensed physicians handle every clinical decision.
Clara auto-syncs from 150,000+ medical sources and reads every prior result, medication, and diagnosis together. A ferritin that was low eight months ago and never rechecked is part of the picture. Clara doesn't miss it.
Clara doesn't anchor on the first plausible cause. It reads fatigue against your full chart and surfaces what the full pattern points to, including combinations that a single-symptom visit is unlikely to catch.
Clara drafts; physicians decide. Every lab order and prescription is reviewed and signed by a licensed clinician. The AI handles intake and reasoning. The physician handles sign-off.
An AI that reads your full chart. A physician who signs off on every clinical decision.
Get started Licensed medical providers review every lab order and prescription.Free to connect your records and chat with Clara. Standard and Concierge plans include physician-reviewed lab orders and bundled biomarker panels that cover the most common causes of persistent fatigue.
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