Semaglutide · Type 2 diabetes

Clara reads your A1C, your meds, and your kidney function before dosing Ozempic.

Clara reads your A1C history, your current medication list, and your wearable glucose data before drafting a starting dose. A physician signs off on every Rx.

Get started How it works

Diabetes monitoring · 12 weeks on Ozempic

Needs review

A1C (current)7.8% ≤6.5% target

A1C (3 months ago)8.3% ≤6.5% target

Current doseOzempic 1 mg weekly unchanged 8 weeks

eGFR62 mL/min/1.73m² stable

Clara: Your A1C improved 0.5 points on Ozempic 1 mg, but is still above target after 8 weeks of stable dosing. I'll draft a titration to 2 mg and a follow-up A1C at 12 weeks for our physician to review.

Values and scenarios shown are illustrative examples only. All clinical assessments are individualized and reviewed by a licensed physician.

How it works

Connect your records. Clara reads the full picture. A physician signs off on every clinical action.

Connect your records

Clara auto-syncs your medical records from 150,000+ doctors' offices, hospitals, labs, and pharmacies: every prior lab, every prescription, every diagnosis. Wearable data syncs automatically on Standard and Concierge plans. Free to start, no credit card.

Clara checks candidacy, interactions, and dose

Before drafting any prescription, Clara reads your full chart: indication, contraindications, every drug and supplement on your list, and any prior trials of this medication. The interaction check runs against the full FDA label — not just the common flagged pairs.

Physician-reviewed Rx, then on-clock monitoring

Every prescription is reviewed and signed off by a licensed physician before it reaches your pharmacy. Clara then tracks the key monitoring labs on schedule — not at your next annual visit — and flags when dose adjustment or follow-up is warranted.

About semaglutide

Semaglutide: what it treats, who it's for, and what Clara reads before prescribing.

FDA-approved indications

✓Type 2 diabetes mellitus in adults, as an adjunct to diet and exercise to improve glycemic control

✓Reduction of risk of major adverse cardiovascular events (CV death, non-fatal MI, non-fatal stroke) in adults with type 2 diabetes and established cardiovascular disease

✓Reduction of risk of sustained eGFR decline, end-stage kidney disease, and CV death in adults with type 2 diabetes and chronic kidney disease

Who Clara evaluates for semaglutide

✓Adults with type 2 diabetes whose A1C is above their individualized target despite metformin or lifestyle interventions

✓Adults with type 2 diabetes and established cardiovascular disease or chronic kidney disease

✓Patients already on a stable Ozempic regimen who need dose review, refills, and on-schedule lab monitoring

✗Patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

What Clara checks

Four things Clara reads before drafting — and keeps reading after.

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Indication and candidacy

Clara reads your A1C trajectory, your fasting glucose, your prior anti-diabetic medications, and your kidney function before confirming Ozempic candidacy. It cross-checks your personal and family history for medullary thyroid carcinoma or MEN 2 syndrome — both contraindications — before drafting.

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Drug and supplement interactions

Ozempic delays gastric emptying and can alter the absorption of co-administered oral medications. Co-administration with insulin or insulin secretagogues (sulfonylureas) increases the risk of hypoglycemia, often requiring a dose reduction of the concomitant drug. Clara reads your full medication list — including thyroid replacement, oral contraceptives, and other diabetes medications — before drafting.

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Dose sizing

Per the Ozempic prescribing information, the starting dose is 0.25 mg subcutaneously once weekly for 4 weeks (for tolerance, not glycemic control), then 0.5 mg weekly. Dose may be increased to 1 mg or 2 mg weekly for further A1C reduction if needed.¹

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On-schedule monitoring

Clara prompts an A1C recheck at 3 months after starting Ozempic or any dose change. Renal function is monitored, particularly during dose escalation and in patients reporting volume-depletion symptoms. Patients on insulin or sulfonylureas are reviewed for hypoglycemia symptoms throughout titration.

Important safety information

Semaglutide (Ozempic) is a prescription medication. The following is a summary of key safety information from the FDA-approved prescribing information. This is not a complete list — see the full prescribing information linked in the footer.

Boxed warning

In rodent studies, semaglutide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors. It is unknown whether Ozempic causes such tumors in humans. Ozempic is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Warnings

Acute pancreatitis (discontinue if suspected). Acute kidney injury (especially with dehydration from GI side effects). Hypoglycemia when used with insulin or sulfonylureas. Diabetic retinopathy complications in patients with a history of retinopathy. Acute gallbladder disease. Hypersensitivity reactions. The most common adverse reactions are nausea, vomiting, diarrhea, abdominal pain, and constipation.

Monitoring requirements

A1C at baseline and every 3 months until at goal. Renal function during dose escalation and with volume-depletion symptoms. Patients on insulin or sulfonylureas should be monitored for hypoglycemia. Patients with a history of diabetic retinopathy should have ophthalmic monitoring.

Special populations

Pregnancy: discontinue Ozempic at least 2 months before a planned pregnancy; safety in human pregnancy is not established. Lactation: limited data; consider risks and benefits. Pediatric: safety and effectiveness in pediatric patients have not been established. Geriatric: no overall dose adjustment, but increased monitoring is reasonable. Renal/hepatic impairment: no dose adjustment recommended; monitor renal function with GI side effects.

Why Clara

How Clara manages Ozempic differently.

	Clara	Cash-pay DTC GLP-1 telehealth	General telehealth	Your doctor
Cost to start	Free (records + chat)	Subscription required	Per-visit fee	$150+ copay
Monthly cost	From $25/mo · Standard $50/mo · HSA/FSA eligible	$199–$299/mo bundled cash-pay	Per-visit, varies	Per-visit copay
Reads full chart before prescribing	✓ Auto-synced, 150,000+ sources	Intake questionnaire only	Self-uploaded only	Within a single practice
Prescribes FDA-approved branded medication (not compounded)	✓ Branded or FDA-approved generic	Often compounded semaglutide	Varies	✓
Prescription may be covered by your insurance	✓	Cash-pay bundled	Varies	✓
On-schedule A1C and kidney monitoring	✓ Ordered on label cadence	Patient-initiated	Patient-initiated	At next visit
Biomarker panel included	✓ 74–108 tests in membership	Extra cost	Extra cost	Per-test copay
Full primary care (beyond diabetes)	✓	Single-vertical	Single-condition	✓

The AI difference

What an AI that reads your full chart makes possible in primary care.

A clinician in a 15-minute visit reads the last panel. Clara reads every result you've ever had drawn — every lab, every wearable reading, every medication change — and cross-references them in a single pass. That's not a time-management difference. It's a category-of-work difference. The AI handles the data; licensed physicians handle every clinical decision.

Reads your entire chart, every time

Clara auto-syncs from 150,000+ medical sources and reads every prior result, medication, and diagnosis together — not just the last visit's notes. Pattern-finding across years of data is what the AI is built for.

Continuous monitoring, not annual snapshots

Clara watches for drift between visits — a creeping lab value, a wearable trend, a new medication interaction — and surfaces it when it's actionable, not when you happen to schedule an appointment.

Physician review on every clinical action

Clara drafts; physicians decide. Every prescription and lab order is reviewed and signed by a licensed clinician before it reaches your pharmacy or lab. The AI handles intake, reasoning, and follow-up. The physician handles sign-off.

Common questions

Semaglutide with Clara: questions patients ask.

What does Clara cost?

Connecting your medical records and chatting with Clara is free. To access physician-reviewed prescriptions and lab orders, plans start at $50/month. Standard ($50/mo) includes 74 biomarker tests, wearable integration, and weekly record sync. Concierge ($150/mo) includes 108 biomarker tests and expanded panels. All plans are HSA/FSA eligible. Biomarker panels are included in the membership — not billed separately and not billed to insurance. Medications and ad-hoc lab orders are billed by your pharmacy or lab and may be covered by your insurance.

Can I use my insurance, HSA, or FSA?

Clara's membership is cash-pay and not billed through insurance, but every plan is HSA/FSA eligible. Prescriptions Clara's physicians write go to your pharmacy and may be covered by your plan like any other script — Clara prescribes FDA-approved branded and generic medications, not compounded formulations. Ad-hoc lab orders may also be covered by your insurance when applicable.

Is Clara a real medical practice?

Yes. Clara operates through affiliated professional corporations licensed in all 50 states. All diagnoses, prescriptions, and lab orders are reviewed and signed off by licensed physicians. Clara's AI handles intake, continuous monitoring, and clinical reasoning — the physician sign-off happens before any clinical action reaches you.

How is this different from my regular doctor?

A 15-minute annual visit can review your most recent results. Clara reads every lab you've had drawn, every medication you've been on, and every wearable data point in a single pass — and does it every time you interact, not just at annual visits. Your PCP remains the right choice for in-person exams, procedures, and anything Clara refers out. Clara fills the continuous monitoring gap between visits.

Is my data private?

Clara is HIPAA compliant. Your medical records and wearable data are used solely to personalize your care. They are not sold to third parties and are not used to train public AI models.

Does Clara prescribe branded Ozempic or compounded semaglutide?

Clara's physicians prescribe FDA-approved branded Ozempic, not compounded semaglutide. Branded Ozempic goes through the standard pharmacy fill and may be covered by your insurance. Compounded semaglutide is a cash-pay product sold by some telehealth brands; Clara does not use it because the FDA has issued safety concerns about compounded GLP-1 formulations and because branded coverage through insurance is the better long-term economics for most patients.

How long will I need to take Ozempic?

Type 2 diabetes is generally a long-term condition, and Ozempic is typically continued as long as it's well-tolerated and the patient is at A1C goal. Stopping Ozempic often leads to A1C rising back toward baseline. Clara monitors your A1C, kidney function, and tolerability throughout, and your physician reviews whether to continue, adjust, or switch at every visit.

What if I'm getting side effects from Ozempic?

Message Clara any time, day or night. Mild nausea and GI side effects are most common in the first weeks and often improve with continued use or with a slower titration. Persistent severe nausea, signs of pancreatitis (severe abdominal pain), or kidney symptoms should be flagged immediately. Clara reads your report against your dose, your refill cadence, and your overall response, drafts a recommendation, and routes it to our physician.