High Cholesterol Treatment Online · AI Primary Care

How it works

Records synced, lipids read in context, plan drafted, then Clara tracks LDL and ApoB on-clock.

Connect your records

Clara auto-syncs your records from 150,000+ doctors' offices, hospitals, labs, and pharmacies. Before anything is prescribed, the AI reads every lipid panel you've had drawn, your blood pressure trend, your A1C, any family history of premature ASCVD, and every medication on your chart. Free, no credit card.

A plan grounded in your data

Clara calculates your 10-year ASCVD risk, interprets ApoB and Lp(a) on top of LDL, and surfaces an on-label statin choice and dose. If a statin isn't right (or you've had side effects on one before), Clara surfaces the alternatives. A licensed physician reviews and signs off.

On-clock retesting

Clara orders a repeat lipid panel at 4–12 weeks after a dose change — on schedule, not at "your next annual". Ad-hoc labs may be covered by your insurance; on Standard and Concierge, a bundled biomarker panel (74 or 108 tests) is included in the membership.

Treatments

Statins dosed to your risk, alternatives when a statin doesn't fit, and the ApoB and Lp(a) work most primary-care visits skip.

Rx · Moderate-intensity statin

Atorvastatin 10–20 mg daily

Moderate-intensity dose. On-label as an adjunct to diet to reduce LDL-C in primary hypercholesterolemia and mixed dyslipidemia, and to reduce the risk of CV events in patients with risk factors. Clara checks ALT, CK if symptomatic, and drug interactions before drafting.

−39%

LDL-C reduction at 10 mg once daily per pooled dose-response data in the Lipitor label¹

Rx · High-intensity statin

Atorvastatin 40–80 mg daily

High-intensity dose. Used for known ASCVD, very high LDL, familial hypercholesterolemia, or when moderate-intensity hasn't taken LDL to goal. Clara flags statin-associated myalgia patterns from your chart and reads any prior trial in context.

−60%

LDL-C reduction at 80 mg once daily per pooled dose-response data in the Lipitor label¹

Rx · Alternative / add-on

Rosuvastatin, ezetimibe, bempedoic acid

When a patient has statin-associated side effects, or when LDL stays above goal on a statin alone. Clara sorts out whether to switch statins, add ezetimibe, or escalate based on your chart — not a generic flowchart.

Add-on therapy for goal-directed LDL

Rx · PCSK9 / specialty

PCSK9 inhibitors for high-risk patients

When LDL stays above goal despite maximally-tolerated statin plus ezetimibe — especially in patients with familial hypercholesterolemia, established ASCVD, or very high Lp(a). Clara surfaces candidacy and coordinates with a preventive cardiology referral when appropriate.

High-risk / refractory LDL

Rx · Cardiometabolic

BP, A1C, and weight work

Cholesterol doesn't live alone. Clara tracks your blood pressure, A1C, weight trend, and ApoB against goal and coordinates the full cardiovascular-risk plan instead of treating each number in its own siloed appointment. For type 2 diabetes with established CVD, a GLP-1 also enters the plan.

Coordinated, not siloed

Supportive · Lifestyle

Nutrition, fiber, and activity

Diet and activity can move LDL meaningfully, especially at borderline risk. Clara builds a realistic plan tied to your lab trajectory and wearable data, not a printed handout. Fasting glucose, resting heart rate, and sleep trends all feed the ApoB plan.

Tracked

Integrated with wearables

Why Clara

ApoB, Lp(a), and statin management handled by an AI reading your whole chart.

	Clara	GoodRx Care	Your doctor
24/7 AI clinical chat	✓ Unlimited	Per-visit consult only	✗
Reads ApoB and Lp(a), not just LDL	✓	Depends on visit request	Depends on visit length
Longitudinal chart across visits	✓ Auto-synced from 150,000+ sources	One-off, per visit	Only within a single practice
Cost to start	Free (records + chat)	$59.99/visit self-pay (or $21.99 with GoodRx Gold)	$150+ copay per visit
Monthly cost	From $25/mo cash-pay membership (HSA/FSA eligible)	Per-visit; no continuity	Per-visit copay
Prescription may be covered by your insurance	✓ FDA-approved branded or generic	✓ (at your pharmacy)	✓
Labs and biomarkers	Ad-hoc labs may be covered by your insurance; 74 (Standard) / 108 (Concierge) biomarker tests included in membership	Not offered	Copay per test
Full primary care, not a single visit	✓	Per-service refill visits	✓

The AI difference

Cholesterol is where "reading the whole chart" pays off most.

LDL is a lossy summary of a richer signal. ApoB is a better estimate of atherogenic particle number. Lp(a) is mostly genetic and almost nobody orders it. A family history of a sibling's early MI should change your statin decision and rarely does. All of that lives in a chart. A 15-minute visit cannot realistically cross-reference it; an AI can.

Reads every prior panel, not just the last one

Clara cross-correlates a decade of lipid panels, your A1C trend, BP trajectory, family history, and medication list in one pass and surfaces the pattern that should drive the decision. A physician scanning the last two panels in 15 minutes cannot do this, no matter how experienced they are.

Interprets ApoB and Lp(a) properly

ApoB-LDL discordance matters; Lp(a) matters; ASCVD risk calculators don't include either natively. Clara reads the primary literature (the label's dose-response tables, preventive cardiology guidelines) and interprets your numbers in that frame, not as a flat ATP-III checklist.

Cross-checks every med against the label

Statin interactions with amlodipine, cyclosporine, clarithromycin, certain antivirals, grapefruit, gemfibrozil — Clara runs the interaction matrix against everything in your chart in seconds before drafting a dose. A busy clinic cannot realistically do this across the whole label every visit.

Common questions

Cholesterol questions patients actually search for.

What does Clara cost?

It's free to connect your medical records and start chatting with Clara. If you want Clara to provide medical advice, prescribe medications, or order labs, plans start at $25/month. All plans are HSA/FSA eligible. The cost of medications and ad-hoc lab work is separate and may be covered by your insurance. On Standard ($50/month) or Concierge ($150/month), a bundled biomarker panel (74 or 108 tests) is included in the membership itself.

How is this different from my regular doctor?

Can your old doctor read every lipid panel you've had drawn in the last decade, your ApoB, your Lp(a), your family history, and every wearable-recorded resting heart rate every time you meet with them? Clara can. A 15-minute visit can eyeball the last panel; Clara cross-correlates the whole picture in one pass. The reading is AI-native, and the follow-up is continuous.

Can I use my insurance, HSA, or FSA?

Clara's membership itself is cash-pay. It's not billed through insurance, but every plan is HSA/FSA eligible, so you can pay it with pre-tax dollars. What the membership sets in motion may be covered by your insurance: atorvastatin, rosuvastatin, ezetimibe, and other prescriptions Clara writes go to your pharmacy and may be covered like any other script, and ad-hoc lab orders (a repeat lipid panel, an ApoB, an Lp(a)) may be covered by your insurance when applicable. Bundled biomarker panels on Standard (74 tests) and Concierge (108 tests) are included in the membership fee itself.

What's the difference between LDL, ApoB, and Lp(a)?

LDL-C measures the cholesterol carried in LDL particles. ApoB measures the number of atherogenic particles directly and is a better estimate of cardiovascular risk when LDL and triglycerides disagree. Lp(a) is a separate, largely genetic risk factor that most primary-care panels never order — elevated Lp(a) raises ASCVD and aortic-valve-disease risk independently of LDL. Clara interprets all three together, not as one number. Our longevity labs panel includes ApoB and Lp(a) by default.

I have muscle aches on statins. Are there alternatives?

Statin-associated muscle symptoms are common and often dose- or drug-specific. Clara reads your prior statin trials, any CK you've had drawn, and interacting medications, and can surface a lower-intensity dose, a switch to a different statin (rosuvastatin, pitavastatin), or non-statin options (ezetimibe, bempedoic acid, PCSK9 inhibitors) in context.

How quickly does cholesterol come down on a statin?

LDL-C begins to drop within 2 weeks of starting a statin and plateaus around 4–6 weeks at a stable dose. Pooled dose-response data from the Lipitor label show approximately −39% LDL-C at 10 mg once daily and up to approximately −60% LDL-C at 80 mg once daily¹. Clara orders the repeat panel at 4–12 weeks after a dose change so the titration decision is data-driven, not "at your next annual".

Is Clara a real medical practice?

Yes. Clara operates through affiliated professional corporations licensed in all 50 states. Diagnoses, prescriptions, and lab orders are reviewed and signed off by licensed physicians. The AI handles intake, continuous monitoring, and follow-up; the clinical sign-off happens at the end.

What if I need in-person care, like a CT coronary calcium scan?

Clara refers you to an in-person provider when imaging, a physical exam, or a procedure is needed — coronary calcium scoring, echocardiography, a specialist cardiology workup for symptomatic disease. Clara handles what can be handled remotely (labs, titration, chart-based reasoning) and coordinates the rest.

Can I use Clara for more than cholesterol?

Yes. One membership covers full primary care — hypertension, type 2 diabetes, thyroid, mental health, sick-day issues, and longevity work. Cardiovascular risk is rarely just a cholesterol problem; the whole plan lives in one place.

Is my data private?

Clara is HIPAA compliant. Your records are used to personalize your care. They're not sold, and they're not used to train public AI models.

An AI that reads your lipid panel the way a preventive cardiologist would.