GLP-1s Online · AI Primary Care for Semaglutide and Tirzepatide

How it works

Chart in, eligibility checked, the right GLP-1 matched to your indication, then Clara tracks A1C, weight, and side effects on-clock.

Connect your records

Clara auto-syncs from 150,000+ doctors' offices, hospitals, labs, pharmacies, and wearables. Before anything is prescribed, the AI reads your A1C trend, BMI, medication list, eGFR, thyroid and family history against the semaglutide and tirzepatide labels. Free, no credit card.

Right GLP-1, right indication

Ozempic and Mounjaro are FDA-approved for type 2 diabetes. Wegovy and Zepbound are approved for chronic weight management. Clara matches the molecule to your indication and flags which option your formulary is most likely to cover. A licensed physician signs off on the prescription.

Sent to your pharmacy, not a compound pharmacy

Clara writes branded FDA-approved medication to your regular pharmacy, where it may be covered by your insurance. DTC competitors like Hims and Lemonaid run a cash-pay model (and often pivot to 503A compounded semaglutide), which keeps the medication off your health plan entirely.

The lineup

Five branded GLP-1s, two molecules, two indications. Clara picks the right one for you.

Rx · Semaglutide · T2D

Ozempic (semaglutide injection)

Once-weekly injectable GLP-1 agonist, FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, and to reduce the risk of major adverse cardiovascular events in adults with T2D and established cardiovascular disease¹. Not approved for chronic weight management.

26%

Relative MACE risk reduction vs. placebo in SUSTAIN 6¹

Rx · Semaglutide · Weight

Wegovy (semaglutide injection)

Same molecule as Ozempic, titrated higher (to 2.4 mg/week). FDA-approved for chronic weight management in adults with BMI ≥30, or BMI ≥27 with a weight-related comorbidity such as hypertension, type 2 diabetes, or dyslipidemia³.

2.4 mg

Maintenance dose once weekly

Rx · Tirzepatide · T2D

Mounjaro (tirzepatide injection)

Once-weekly dual GIP/GLP-1 agonist, FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes². The dual-agonist mechanism typically produces larger A1C and weight reductions than semaglutide alone.

−2.4%

A1C reduction at 15 mg in SURPASS-4 at 52 weeks²

Rx · Tirzepatide · Weight

Zepbound (tirzepatide injection)

Same molecule as Mounjaro. FDA-approved for chronic weight management, and for moderate-to-severe obstructive sleep apnea in adults with obesity⁴. Titrates from 2.5 mg to 15 mg weekly.

15 mg

Maximum maintenance dose

Rx · Semaglutide · Oral

Rybelsus (oral semaglutide)

Once-daily oral semaglutide, FDA-approved for type 2 diabetes⁵. A reasonable option if an injectable is a non-starter, with the caveat that the absorption window is narrow: 30 minutes before the first food, drink, or oral medication of the day.

7/14 mg

Titration steps, once daily

Rx · Often paired

Metformin

Oral first-line therapy for type 2 diabetes. Most patients on a GLP-1 for T2D stay on metformin; it's cheap, well-studied, and tends to blunt the cardiovascular and renal risk stack. Clara reconciles both scripts against your eGFR and B12 before calling in the prescription.

−1.12%

Mean A1C reduction vs. placebo (meta-analysis, 35 trials)⁶

Why Clara

Branded FDA-approved GLP-1s written to your pharmacy, not compounded semaglutide sold cash-pay.

	Clara	Hims & Hers	Lemonaid Health	Your doctor
24/7 AI clinical chat	✓ Unlimited	Async Care Team messaging	Async provider messaging	✗
Matches the GLP-1 to your FDA-approved indication	✓ Every prescription	Weight-loss channel only	Per-category intake	Depends on visit length
Cost to start chatting	Free	$39 first-month membership	Brief eligibility assessment	$150+ copay per visit
Membership cost	From $25/mo cash-pay (HSA/FSA eligible); medication billed separately, may be covered by your insurance	$149/mo after first month; medication bundled, cash-pay	$49/mo; medication billed separately, cash-pay	Per-visit copay
Branded Wegovy written to your pharmacy	✓	From $199/mo cash on top of membership	Sold alongside compounded semaglutide, cash-pay	✓
Branded Mounjaro / Zepbound written to your pharmacy	✓	From $1,899/mo cash on top of membership	Zepbound vials or compounded tirzepatide, cash-pay	✓
Prescription may be covered by your insurance	✓	✗	✗	✓
Cross-condition reasoning (BP, lipids, thyroid, drug interactions)	✓	Single-condition	Per-intake siloes	In theory, rarely in 15 minutes
Full primary care, not just weight loss	✓	Single-category	Partial, separate intakes	✓
Labs and biomarkers included in membership	Up to 108 on Concierge	Extra cost	Extra cost	Copay per test

The AI difference

A GLP-1 prescription is only as safe as the chart behind it. Clara reads the whole chart.

The real mistakes in GLP-1 care are almost never about the molecule. They're about what else is in your record: the family history of medullary thyroid cancer nobody asked about, the statin that's silently pushing your liver enzymes, the insulin dose that starts causing hypoglycemia the week Mounjaro lands, the formulary rule that makes Wegovy free while Zepbound costs you $1,800.

Indication matched to the label

Ozempic is not Wegovy. Mounjaro is not Zepbound. Clara reads your A1C, BMI, and comorbidity list against each label and flags which GLP-1 is actually on-label for you, then picks the variant most likely to be covered by your formulary.

Contraindication pass against your full chart

Medullary thyroid cancer family history, MEN 2, pancreatitis history, diabetic retinopathy, eGFR trend, pregnancy plans, concurrent insulin or sulfonylurea. Clara runs the full label contraindication list in seconds. A 15-minute visit physically cannot.

Titration against the trend, not the calendar

Clara watches your home glucose, your A1C, your weight trajectory, and your GI-side-effect pattern, and flags exactly when to step from 0.25 mg to 0.5 mg to 1 mg (or 2.5 mg to 5 mg to 7.5 mg on tirzepatide). Repeat labs are on-clock, not at the next annual visit.

Common questions

GLP-1 questions patients actually search for.

What does Clara cost?

It's free to connect your medical records and start chatting with Clara. If you want Clara to provide medical advice, prescribe medications, or order labs, plans start at $25/month. All plans are HSA/FSA eligible. The cost of GLP-1 medication and lab work is separate and may be covered by your insurance, unlike the cash-pay model Hims and Lemonaid use for GLP-1s, which keeps the medication off your health plan entirely.

What's the difference between Ozempic, Wegovy, Mounjaro, and Zepbound?

Ozempic and Wegovy are both semaglutide from Novo Nordisk. Ozempic is approved for type 2 diabetes (up to 2 mg/week); Wegovy is approved for chronic weight management (up to 2.4 mg/week). Mounjaro and Zepbound are both tirzepatide from Eli Lilly (a dual GIP/GLP-1 agonist). Mounjaro is approved for T2D; Zepbound is approved for chronic weight management and for moderate-to-severe obstructive sleep apnea in adults with obesity. Clara matches the right molecule to your indication and flags which one your insurance formulary is most likely to cover.

Can I get a GLP-1 just for weight loss if I'm not diabetic?

Yes, but the right molecule for you is Wegovy or Zepbound, not Ozempic or Mounjaro. Wegovy is FDA-approved for adults with BMI ≥30, or BMI ≥27 with a weight-related comorbidity such as hypertension, type 2 diabetes, or dyslipidemia³. Zepbound is approved under similar BMI criteria and also for moderate-to-severe obstructive sleep apnea in adults with obesity⁴. Clara reads your BMI, your comorbidities, and your formulary before picking one.

What if I have a family history of medullary thyroid cancer or MEN 2?

All four branded GLP-1s (Ozempic, Wegovy, Mounjaro, Zepbound) carry a boxed warning about thyroid C-cell tumors and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)¹². Clara asks explicitly about first-degree family history before any GLP-1 is drafted; if the flag is positive, a non-GLP-1 plan is surfaced instead.

Why is branded medication through Clara cheaper than through Hims or Lemonaid?

Because Clara prescribes FDA-approved branded medication to your regular pharmacy, where it may be covered by your insurance like any other script. Hims and Lemonaid sell cash-pay: Hims lists Wegovy Pen at $199/mo and branded Zepbound at roughly $1,899/mo, on top of a $149/mo membership. That's the price of not routing through insurance. For many patients, a Clara prescription filled under their insurance plan comes in well below either tier.

How quickly will I see results on a GLP-1?

A1C reflects about three months of blood glucose, so meaningful reductions on Ozempic or Mounjaro are typically visible at the 3-month repeat lab once you've reached a maintenance dose. Weight reductions on Wegovy and Zepbound trail off over 16 to 72 weeks as the dose titrates up; the large pivotal trials (STEP-1 for Wegovy, SURMOUNT-1 for Zepbound) measured outcomes at 68 and 72 weeks. Clara orders the repeat labs on-clock rather than at the next annual visit.

Is Clara a real medical practice?

Yes. Clara is licensed in all 50 states. Diagnoses, prescriptions, and lab orders are reviewed and signed off by licensed physicians. Clara's AI handles intake, continuous monitoring, and follow-up; the clinical sign-off happens at the end.

How is this different from my regular doctor or a GLP-1 telehealth brand?

Can your old doctor read your entire medical chart and look at all your labs and wearable data every time you meet with them? Clara can. And can a single-condition weight-loss brand tell you that your new semaglutide is quietly slowing the absorption of your levothyroxine, or that your potassium ran high the week you started a diuretic? A single-condition brand does not have those charts at all. Clara is full primary care with a longitudinal view, which is the piece both traditional clinics and GLP-1 storefronts miss.

Can I use my insurance, HSA, or FSA?

Clara's membership itself is cash-pay, not billed through insurance, but every plan is HSA/FSA eligible so you can pay it with pre-tax dollars. What the membership puts in motion may be covered by your insurance: prescriptions Clara writes go to your pharmacy and may be covered by your plan like any other script, and Clara deliberately prescribes branded FDA-approved semaglutide and tirzepatide (not cash-pay compounded formulations) so they stay eligible for standard insurance coverage. Ad-hoc lab orders Clara places may also be covered.

What is my data used for? Is it private?

Clara is HIPAA compliant. Your records are used to personalize your care. They're not sold, and they're not used to train public AI models.

What if Clara can't help me, or I need in-person care?

Clara refers you to an in-person provider when a physical exam, imaging, or in-person procedure is needed, for example a diabetic eye exam, a cardiac workup before starting a GLP-1 with established CV disease, or bariatric evaluation at higher BMIs. The AI handles what can be handled remotely; in-person care happens in person.

Can I use Clara for other health issues too?

Yes. One membership covers full primary care, not just GLP-1 care. The same chat handles your blood pressure, cholesterol, thyroid, annual labs, sick-day questions, and longevity work. That's the whole point of primary care, and it's what single-condition GLP-1 brands can't offer by design.

Care that knows which GLP-1 fits your chart, and which one fits your insurance.