Atorvastatin · HMG-CoA reductase inhibitor

Care that knows when your LDL needs 20 mg, and when it needs 80.

Care that reads every lipid panel on your chart and drafts the right atorvastatin dose. Our physician signs off.

Lipid panel · April

Attention

LDL-C: 172mg/dL(<100)
HDL-C: 48mg/dL(>40)
Triglycerides: 138mg/dL(<150)
10-year ASCVD risk: 14.8%(>7.5% = Rx)

Clara's draft → Atorvastatin 40 mg daily (high-intensity). Est. LDL drop ~50% with a lipid recheck in 6 to 8 weeks. Sent to our physician to sign off.

How it works

A statin prescribed from your chart, not a generic recommendation.

Connect your chart

Clara auto-syncs your records from 150,000+ doctors' offices, hospitals, labs, and wearable devices. Every prior lipid panel, every medication, your BP, and your diabetes status — all read. Free.

Clara reasons across your full context

Clara calculates your 10-year ASCVD risk, applies the ACC/AHA guideline, screens for interactions (amlodipine + simvastatin, macrolides, azoles), and drafts the right atorvastatin dose². A licensed physician reviews and signs off.

Titrate to your LDL goal, not to a visit

Clara drafts a follow-up lipid panel at 6 to 8 weeks, reads the result, and drafts a dose step-up, ezetimibe add-on, or PCSK9 referral if you haven't hit goal.

Try Clara before you fill your next statin refill.

Get startedFree to start. No credit card required.

How Clara uses atorvastatin

Moderate- and high-intensity dosing, add-ons, and when to switch.

Rx · Moderate intensity

Atorvastatin 10–20 mg

Moderate-intensity dose expected to lower LDL by 30–49%². Usual choice for primary prevention in intermediate-risk patients when a high-intensity dose is not needed.

~35%

Expected LDL reduction²

Rx · High intensity

Atorvastatin 40–80 mg

High-intensity dose expected to lower LDL by ≥50%². On-label for established cardiovascular disease, LDL ≥190, or diabetes with elevated risk. TNT trial: 80 mg vs 10 mg reduced major CV events by 22% in stable CHD³.

≥50%

Expected LDL reduction²

Rx · Secondary prevention

Post-stroke or TIA

In SPARCL, atorvastatin 80 mg reduced recurrent fatal or nonfatal stroke by 16% in patients with a recent stroke or TIA and no known CHD⁴.

16%

Relative stroke reduction in SPARCL⁴

Rx · Add-on

Ezetimibe 10 mg

When high-intensity atorvastatin still leaves LDL above goal, adding ezetimibe lowers LDL by an additional ~20%⁵. Clara drafts the add-on as part of the plan.

~20%

Additional LDL reduction with ezetimibe⁵

Safety · Interactions

No simvastatin-style cap

Unlike simvastatin, atorvastatin does not have the <20 mg cap when combined with amlodipine. That makes it the preferred statin for patients on a CCB — something Clara auto-checks against your chart⁶.

No cap

With amlodipine

Monitoring · Labs

Lipid recheck + baseline LFTs

Clara drafts a baseline liver panel before starting and a follow-up lipid panel at 6 to 8 weeks. Ad-hoc lab orders at Labcorp or Quest may be covered by your insurance.

6–8 wk

Follow-up lipid window

Why Clara

Can your old doctor read your entire chart every time?

	Clara	GoodRx Care	Circle Medical	Your doctor
24/7 AI clinical chat with full-chart reasoning	Unlimited	Per-visit only	Visit-based	✗
ASCVD risk calc + guideline check before Rx	Every time	Not automated	Not automated	Dependent on time
Cost to start	Free (connect records + chat)	$49 per cholesterol refill visit	$179 first visit self-pay	$150+ copay
Paid plans	$25/mo membership, HSA/FSA eligible	No membership, $49/visit ($19 w/ GoodRx Gold)	No membership, $120 follow-up self-pay	Per-visit copay
Prescription fills	FDA-approved generic, may be covered by your insurance	Sent to your pharmacy	Sent to your pharmacy	Sent to your pharmacy
Follow-up lipid panel at 6–8 weeks	Drafted automatically	Separate visit	Ordered at visit	Copay applies
Full primary care in one membership		Single-visit refill

GoodRx writes the refill. Clara reads the lipid panel, the liver enzymes, and the next eight weeks.

Get startedFree to connect your chart. HSA and FSA eligible.

The AI difference

A statin that knows your heart, your liver, and the rest of your pill bottle.

The right statin dose is not a lookup — it's a calculation across ten variables. Clara runs that calculation every time, on your actual chart, and tracks the response.

ASCVD risk score, auto-calculated

Clara pulls your BP, diabetes status, smoking status, HDL, total cholesterol, age, race, and sex straight from your chart, runs the pooled cohort equation, and drafts the dose that matches the guideline to your score.

Interaction matrix on every prescription

Erythromycin, clarithromycin, itraconazole, amiodarone, grapefruit — and on simvastatin, amlodipine. Clara reads your med list against the atorvastatin label every time and drafts around conflicts, so they don't show up at the pharmacy.

Titrates to your LDL, not to your calendar

A typical patient gets a statin and doesn't hit LDL goal. Clara re-reads your 8-week lipid panel, drafts a dose step-up or ezetimibe add-on, and flags PCSK9 candidacy for familial hypercholesterolemia — all without a new visit.

Care that reads your ASCVD score, your LDL trend, and every prior lipid panel.

Get startedFree to start. Connect your records in two minutes.

Common questions

Atorvastatin questions patients ask.

How is Clara different from a single refill visit?

A refill visit hands you a prescription and sends you home. Clara keeps reading — your lipid panel, your liver enzymes, any muscle symptoms you mention, and every other condition on your chart. If LDL is still above goal at 8 weeks, or a new medication introduces an interaction, Clara flags it and drafts a response. That is a category of continuous reasoning a one-off visit cannot do.

Do I really need a statin?

The 2018 ACC/AHA cholesterol guideline recommends a statin when your LDL is ≥190, you have known cardiovascular disease, or your 10-year ASCVD risk is ≥7.5%². Clara calculates your ASCVD score from your chart and flags where you sit on the guideline, so you can have an informed conversation about whether a statin is right for you.

What about muscle pain?

Muscle pain is a well-known concern, but randomized data suggests the attributable rate is much lower than reported: the SAMSON trial found that most muscle symptoms on statin occurred on placebo too⁷. Clara checks in at the 6-week mark; if symptoms appear, the options are a dose reduction, a switch to rosuvastatin, or alternate-day dosing.

Does atorvastatin cause diabetes?

Statins modestly increase the risk of new-onset type 2 diabetes (roughly 1 extra case per 1,000 patient-years on moderate-intensity, more on high-intensity), but the cardiovascular benefit substantially outweighs this risk in patients who meet the treatment threshold⁸. Clara tracks your A1c when drafting a statin in someone with prediabetes.

Can I take atorvastatin with my BP meds?

Yes, with one common caveat — atorvastatin has no dose cap when combined with amlodipine, unlike simvastatin, which the FDA limits to 20 mg daily with amlodipine⁶. That's one reason Clara often prefers atorvastatin for patients on a calcium channel blocker. It pairs fine with lisinopril, losartan, and HCTZ.

Is Clara a real medical practice?

Yes. Clara is licensed in all 50 states and operates through affiliated professional corporations. A licensed physician reviews and signs off on every prescription and lab order Clara's AI drafts. Clara's AI handles intake, monitoring, and follow-up; physicians provide medical oversight.

What does Clara cost, and can I use insurance?

Connecting records and chatting with Clara is free. Paid plans start at $25/month for medical advice, prescriptions, and lab orders. All plans are HSA/FSA eligible. Clara's membership is cash-pay and not billed through insurance. Prescriptions Clara writes go to your pharmacy and may be covered by your insurance, and ad-hoc lab orders may be covered by your insurance, depending on your plan. On the Standard and Concierge plans, broad biomarker panels (61 tests or 78 tests) are included in the membership.

Can I use Clara for other health issues too?

Yes. One membership covers full primary care. Most patients on a statin are also managing hypertension or type 2 diabetes; Clara's AI connects the dots across all of them and uses your lab history as one data layer. See longevity labs for the broader panel that Clara can watch on your membership.

Your LDL goal turned into a dose, by the AI that reads your whole chart.

Connect your records, chat with Clara for free, and see whether atorvastatin is the right statin at the right dose for your chart.

Get started

Atorvastatin labeled risks include myopathy and rhabdomyolysis (rare), hepatic dysfunction, and modestly increased risk of new-onset type 2 diabetes. Contraindicated in active liver disease and pregnancy. Lipitor is a registered trademark of Pfizer Inc.

For important safety information about atorvastatin, see the FDA Medication Guide and prescribing information: Atorvastatin. For mentioned alternatives, see Amlodipine, Lisinopril, Losartan, and Hydrochlorothiazide.

¹Lipitor (atorvastatin calcium) tablets: FDA-approved prescribing information. Indications from Section 1 (primary hypercholesterolemia, mixed dyslipidemia, dysbetalipoproteinemia, homozygous familial hypercholesterolemia, primary prevention in patients at elevated CV risk, and secondary prevention). Dosing from Section 2 (10 mg, 20 mg, 40 mg, or 80 mg once daily). View DailyMed labels.

²Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol. J Am Coll Cardiol. 2019;73(24):e285–e350. Moderate-intensity statins (e.g., atorvastatin 10–20 mg) expected to lower LDL by ~30–49%; high-intensity statins (atorvastatin 40–80 mg, rosuvastatin 20–40 mg) expected to lower LDL by ≥50%. View on PubMed.

³LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease (TNT). N Engl J Med. 2005;352(14):1425–1435. Atorvastatin 80 mg vs 10 mg reduced the primary composite endpoint (first major CV event) by 22% (HR 0.78, 95% CI 0.69–0.89, p<0.001) in 10,001 stable CHD patients. View on PubMed.

⁴Amarenco P, Bogousslavsky J, Callahan A 3rd, et al. High-dose atorvastatin after stroke or transient ischemic attack (SPARCL). N Engl J Med. 2006;355(6):549–559. Atorvastatin 80 mg reduced the primary endpoint of first nonfatal or fatal stroke by 16% (HR 0.84, 95% CI 0.71–0.99, p=0.03) in 4,731 patients with recent stroke/TIA and no known CHD. View on PubMed.

⁵Cannon CP, Blazing MA, Giugliano RP, et al. Ezetimibe added to statin therapy after acute coronary syndromes (IMPROVE-IT). N Engl J Med. 2015;372(25):2387–2397. Addition of ezetimibe 10 mg to simvastatin lowered LDL further and reduced the primary composite CV endpoint by 6.4% over 7 years. View on PubMed.

⁶Zocor (simvastatin) prescribing information, Section 5.1: simvastatin dose limited to 20 mg/day with amlodipine due to increased myopathy risk. Atorvastatin prescribing information does not contain an equivalent amlodipine dose restriction. View DailyMed label.

⁷Wood FA, Howard JP, Finegold JA, et al. N-of-1 trial of a statin, placebo, or no treatment to assess side effects (SAMSON). N Engl J Med. 2020;383(22):2182–2184. In blinded crossover, 90% of the symptom intensity attributed to statin by patients occurred when they were taking placebo tablets too. View on PubMed.

⁸Sattar N, Preiss D, Murray HM, et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010;375(9716):735–742. Statin therapy was associated with a 9% increased risk of new-onset diabetes (OR 1.09, 95% CI 1.02–1.17); cardiovascular benefit outweighed this risk in patients meeting treatment thresholds. View on PubMed.